Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.69 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29889164 | 0.83 | TDP1 (1.00) | TDP1HSD17B10TP53ERN1ALDH1A1 | |
| SCHEMBL95435 | 0.83 | TDP1 (1.00) | TDP1HSD17B10TP53ERN1ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL8037724 | 0.81 | TDP1 (0.95) | TDP1HSD17B10TP53ERN1ALDH1A1 | |
| SCHEMBL8070590 | 0.81 | CYP2A6 (0.76) | TDP1CYP2A6HSD17B10ALDH1A1MAOA | |
| SCHEMBL28153636 | 0.81 | CYP2A6 (0.76) | TDP1CYP2A6HSD17B10ALDH1A1MAOA | |
| SCHEMBL29952819 | 0.79 | TDP1 (0.61) | TDP1CYP2A6ERN1ALDH1A1MAPT | |
| SCHEMBL4268830 | 0.79 | TDP1 (0.61) | TDP1CYP2A6ERN1ALDH1A1MAPT | |
| SCHEMBL3122359 | 0.77 | ALDH1A1 (0.67) | TDP1CYP2A6HSD17B10TTRERN1 | |
| SCHEMBL30493606 | 0.77 | ALDH1A1 (0.67) | TDP1CYP2A6HSD17B10TTRERN1 | |
| SCHEMBL8035343 | 0.77 | TDP1 (0.53) | TDP1CYP2A6HSD17B10ERN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6028182-A | Methylphosphonic acid esters, processes for their preparation, and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-02-22 | — | — | US | disclosed |