Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.59 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LTA4H | P09960 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10674754 | 0.98 | HRH3 (0.56) | HRH3HRH4ALDH1A1KDM4ELTA4H | |
| Formic Acid SCHEMBL28851183 | 0.90 | HRH3 (0.48) | HRH3HRH4ALDH1A1KDM4ELTA4H | |
| SCHEMBL3373813 | 0.83 | CHRM2 (0.50) | HRH3ALDH1A1CYP2D6CYP2C19LMNA | |
| SCHEMBL13041009 | 0.82 | MC4R (0.58) | ALDH1A1KDM4ELMNATDP1 | |
| SCHEMBL30269770 | 0.81 | HRH3 (0.56) | HRH3LTA4HMBTD1L3MBTL3L3MBTL1 | |
| SCHEMBL11381001 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNA | |
| SCHEMBL4701933 | 0.81 | ALDH1A1 (0.48) | ALDH1A1KDM4ELTA4HLMNA | |
| SCHEMBL3975858 | 0.81 | HRH3 (0.56) | HRH3ALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL2264365 | 0.81 | SIGMAR1 (0.56) | HRH3ALDH1A1TDP1 | |
| SCHEMBL31010302 | 0.80 | HRH3 (0.70) | HRH3HRH4ALDH1A1KDM4ECYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563092-A | It can be used as the 2- phenylimidazole of the active inhibitor of mammal tyrosine kinase ROR1 simultaneously [4,5-B] pyridine -7- amine derivative | 坎塞拉有限公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-107567445-A | It can be used as 2 phenyl 3H imidazos [4,5 B] pyridine derivates of mammal EGFR-TK ROR1 activities inhibitor | 坎塞拉有限公司 | 2018-01-09 | — | — | CN | disclosed |
| CN-102803227-A | Morpholinyl quinazolines | MERCK PATENT GMBH | 2012-11-28 | — | — | CN | disclosed |
| WO-2012036997-A1 | FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS | SCHERING CORPORATION (US) | 2012-03-22 | — | — | WO | disclosed |
| CN-100422151-C | Diarylmethylidene piperidine derivatives, their preparation and their use | ASTRAZENECA AB (SE) | 2008-10-01 | — | — | CN | disclosed |
| CN-1738801-A | Diarylmethylidene piperidine derivatives, their preparation and their use | ASTRAZENECA AB (SE) | 2006-02-22 | — | — | CN | disclosed |
| US-5610303-A | MONOAMIDE OXIDASE INHIBITORS | UBE INDUSTRIES, LTD. (JP) | 1997-03-11 | — | — | US | disclosed |