SCHEMBL13041009

SCHEMBL13041009

CN1CCN(Cc2ccsc2)CC1

nearest known ligand 0.58

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MC4R P32245 1/20 0.58
ALDH1A1 P00352 3/20 0.56
LMNA P02545 3/20 0.55
CHKA P35790 4/20 0.51
CA2 P00918 1/20 0.49
NCF1 P14598 1/20 0.49
PRMT6 Q96LA8 1/20 0.49
KDM4E B2RXH2 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
KDR P35968 2/20 0.45
KIT P10721 1/20 0.45
FLT1 P17948 1/20 0.45
FLT4 P35916 1/20 0.45
TEK Q02763 1/20 0.45
HDAC6 Q9UBN7 1/20 0.45
MAPT P10636 1/20 0.45
NPC1 O15118 1/20 0.44
TP53 P04637 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10674754 0.84 HRH3 (0.56) ALDH1A1LMNANCF1PRMT6KDM4E
SCHEMBL11381001 0.83 ALDH1A1 (0.51) MC4RALDH1A1LMNAKDM4E
SCHEMBL807355 0.82 HRH3 (0.59) ALDH1A1LMNAKDM4ETDP1
SCHEMBL14375210 0.80 ACHE (0.59) ALDH1A1LMNA
SCHEMBL12551210 0.80 KMT2A (0.56) ALDH1A1LMNAKDM4EMAPTNPC1
SCHEMBL4701933 0.79 ALDH1A1 (0.48) ALDH1A1LMNAKDM4E
SCHEMBL3975858 0.79 HRH3 (0.56) ALDH1A1LMNANCF1KDM4EMAPT
SCHEMBL2264365 0.79 SIGMAR1 (0.56) ALDH1A1TDP1
SCHEMBL11391691 0.79 ALDH1A1 (0.48) ALDH1A1LMNAKDM4E
SCHEMBL17967808 0.77 SIGMAR1 (0.49) ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240174867-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2024-05-30 US claimed
EP-4301817-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-Desoto International, Inc. (US) 2024-01-10 EP claimed
WO-2022187845-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2022-09-09 WO claimed
US-12577412-B2 Corrosion inhibiting coating compositions PRC-DESOTO INTERNATIONAL, INC. (US) 2026-03-17 US disclosed
WO-2025151695-A1 COATING COMPOSITIONS COMPRISING MAGNESIUM OXIDE AND A LITHIUM COMPOUND PRC-DESOTO INTERNATIONAL, INC. (US) 2025-07-17 WO disclosed
US-20240174867-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2024-05-30 US disclosed
EP-4301817-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-Desoto International, Inc. (US) 2024-01-10 EP disclosed
CN-117321150-A Corrosion inhibiting coating composition PRC-迪索托国际公司 2023-12-29 CN disclosed
WO-2022187845-A1 CORROSION INHIBITING COATING COMPOSITIONS PRC-DESOTO INTERNATIONAL, INC. (US) 2022-09-09 WO disclosed
US-9212147-B2 Dihydroxy aromatic heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-12-15 US disclosed
US-9212147-B2 Dihydroxy aromatic heterocyclic compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2015-12-15 US disclosed
US-7829568-B2 Substituted 5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-ylamine compounds and their use for producing drugs GRUENENTHAL GMBH (DE) 2010-11-09 US disclosed
US-7829568-B2 Substituted 5,6,7,8-tetrahydroimidazo[1,2-a]pyridin-2-ylamine compounds and their use for producing drugs GRUENENTHAL GMBH (DE) 2010-11-09 US disclosed
EP-1869038-B1 SUBSTITUTED 5,6,7,8-TETRAHYDRO-IMIDAZO[1,2-A]PYRIDIN-2-YLAMINE COMPOUNDS AND THEIR USE FOR PRODUCING DRUGS GRUENENTHAL GMBH (DE) 2009-07-08 EP disclosed
US-20080300256-A1 Substituted 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-2-ylamine Compounds and Their Use for Producing Drugs GRUENENTHAL GMBH (DE) 2008-12-04 US disclosed
US-20080300256-A1 Substituted 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-2-ylamine Compounds and Their Use for Producing Drugs GRUENENTHAL GMBH (DE) 2008-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080300256-A1 Substituted 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-2-ylamine Compounds and Their Use for Producing Drugs CYP3A7, CYP3A5, CYP2D6 MC4R 1684/4885ALDH1A1 538/4885LMNA 100/4885
US-12577412-B2 Corrosion inhibiting coating compositions MGMT, MBD2, MECP2 MC4R 422/4885ALDH1A1 897/4885LMNA 4468/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.