Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5515200 | 0.83 | ALDH1A1 (0.47) | PKMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL7822888 | 0.81 | ALDH1A1 (0.41) | ALDH1A1KDM4EMEN1KMT2ATNF | |
| SCHEMBL8057843 | 0.78 | ALDH1A1 (0.42) | PKMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL5514536 | 0.78 | ALDH1A1 (0.42) | PKMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10429039 | 0.77 | DHFR (0.49) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL8067005 | 0.74 | PDK1 (0.38) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL7815755 | 0.74 | RECQL (0.40) | PKMALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8068471 | 0.73 | ALDH1A1 (0.36) | ALDH1A1KDM4EMEN1KMT2ALMNA | |
| SCHEMBL10428913 | 0.73 | POLB (0.44) | PKMKDM4EMEN1KMT2ALMNA | |
| SCHEMBL7823532 | 0.72 | MAPT (0.42) | ALDH1A1KDM4EKMT2ALMNATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1066148-C | Tricyclic benzazepine compounds | MEIJI SEIKA CO (JP) | 2001-05-23 | — | — | CN | disclosed |
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |
| CN-1190971-A | Tricyclic benzazepine * compounds | MEIJI SEIKA CO (JP) | 1998-08-19 | — | — | CN | disclosed |
| EP-0834512-A1 | TRICYCLIC BENZAZEPINE COMPOUNDS | MEIJI SEIKA KAISHA LTD. (JP) | 1998-04-08 | — | — | EP | disclosed |