SCHEMBL8073589

SCHEMBL8073589

CC1=Cc2c(-c3c(C)cc(C)cc3C)cccc2C1[SiH3]

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CRHR1 P34998 1/20 0.32
PDK2 Q15119 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5837337 0.81
Hydrochloric Acid SCHEMBL5837333 0.80 CRHR1 (0.31) CRHR1PDK2
SCHEMBL1453207 0.79 CRHR1 (0.33) CRHR1
Hydrochloric Acid SCHEMBL4460249 0.76 PDK2 (0.30) PDK2
Hydrochloric Acid SCHEMBL5837286 0.76
SCHEMBL6911211 0.76 PDCD1 (0.36)
SCHEMBL5837614 0.74
SCHEMBL142157 0.74
SCHEMBL9421537 0.72 UGT2B17 (0.32)
SCHEMBL28529430 0.72 ALDH1A1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1015463-A1 METHOD FOR PRODUCING METALLOCENES Basell Polyolefine GmbH (DE) 2000-07-05 EP disclosed
WO-1999012943-A1 METHOD FOR PRODUCING METALLOCENES TARGOR GMBH (DE) 1999-03-18 WO disclosed