Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22401709 | 0.83 | BRD4 (0.34) | BRD4 | |
| SCHEMBL7197741 | 0.81 | — | — | |
| SCHEMBL5694274 | 0.81 | PDCD1 (0.37) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| Hydrochloric Acid SCHEMBL28418788 | 0.81 | KIF11 (0.33) | BRD4ALDH1A1 | |
| SCHEMBL7199073 | 0.80 | — | — | |
| SCHEMBL7053161 | 0.80 | PDCD1 (0.34) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL4603520 | 0.79 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL7525652 | 0.79 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL7030356 | 0.79 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 | |
| SCHEMBL27478125 | 0.79 | PDCD1 (0.36) | PDCD1CD274CHRNB2CHRNA4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117624211-A | Separation and purification method of dimethyl di (2-methyl-4-phenyl indenyl) silane ligand | 江苏雅克科技股份有限公司 | 2024-03-01 | — | — | CN | claimed |
| US-20240109923-A1 | TRANSITION METAL COMPOUND AND CATALYST COMPOSITION COMPRISING THE SAME | LG CHEM, LTD. (KR) | 2024-04-04 | — | — | US | disclosed |
| CN-117659101-A | Synthesis method of racemosilicon bridged metallocene catalyst | 江苏雅克科技股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-117624211-A | Separation and purification method of dimethyl di (2-methyl-4-phenyl indenyl) silane ligand | 江苏雅克科技股份有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-117467055-A | Metallocene catalyst and preparation method and application thereof | 中化学科学技术研究有限公司 | 2024-01-30 | — | — | CN | disclosed |
| CN-110546171-B | Catalyst system for forming multi-block copolymers | 陶氏环球技术有限责任公司 | 2023-02-28 | — | — | CN | disclosed |
| CN-115260366-A | Catalyst system for forming multi-block copolymers | 陶氏环球技术有限责任公司 | 2022-11-01 | — | — | CN | disclosed |
| CN-110603274-B | Catalyst system for forming multi-block copolymers | 陶氏环球技术有限责任公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-110612315-B | Catalyst system for forming multi-block copolymers | 陶氏环球技术有限责任公司 | 2022-08-26 | — | — | CN | disclosed |
| CN-110582518-B | Catalyst system for forming multi-block copolymers | 陶氏环球技术有限责任公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-103102442-A | Method for selecting polymerization modifiers | Dow Global Technologise LLC | 2013-05-15 | — | — | CN | disclosed |
| CN-101142247-A | Pseudo-block copolymers and methods of using chain shuttling agents | DOW GLOBAL TECHNOLOGIES INC (US) | 2008-03-12 | — | — | CN | disclosed |
| CN-1954005-A | Catalyst composition comprising shuttling agent for ethylene multi-block copolymer formation | DOW GLOBAL TECHNOLOGIES INC (US) | 2007-04-25 | — | — | CN | disclosed |
| EP-1421375-A2 | METHOD AND APPARATUS FOR DETERMINATION OF WATER AND FOR NORMAL PHASE LIQUID CHROMATOGRAPHY | DOW GLOBAL TECHNOLOGIES INC. (US) | 2004-05-26 | — | — | EP | disclosed |
| CN-1120168-C | Catalyst activators comprising expanded anions | DOW WORLDWIDE TECHNOLOGY INC (US) | 2003-09-03 | — | — | CN | disclosed |
| WO-2003019176-A2 | METHOD AND APPARATUS FOR DETERMINATION OF WATER AND FOR NORMAL PHASE LIQUID CHROMATOGRAPHY | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-03-06 | — | — | WO | disclosed |
| EP-1189950-A1 | SUPPORT CATALYST FOR OLEFIN POLYMERIZATION | Basell Polyolefine GmbH (DE) | 2002-03-27 | — | — | EP | disclosed |
| CN-1290267-A | Catalyst activators comprising expanded anions | DOW CHEMICAL CO (US) | 2001-04-04 | — | — | CN | disclosed |
| CN-1289343-A | Improved olefin polymerization process | DOW CHEMICAL CO (US) | 2001-03-28 | — | — | CN | disclosed |
| WO-2000078823-A1 | SUPPORT CATALYST FOR OLEFIN POLYMERIZATION | BASELL POLYOLEFINE GMBH (DE) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240109923-A1 | TRANSITION METAL COMPOUND AND CATALYST COMPOSITION COMPRISING THE SAME | PCNA, EMG1, TAF1 | PDCD1 2182/4885CD274 2865/4885CHRNB2 4283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.