Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | DCLRE1B | Q9H816 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.34 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.34 |
| ▸ | ITGAL | P20701 | 2/20 | 0.34 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074144 | 0.87 | ACMSD (0.40) | AKR1C3AKR1C2FFAR1PTGS2PDCD1 | |
| SCHEMBL8075216 | 0.87 | ACMSD (0.40) | AKR1C3AKR1C2FFAR1PTGS2PDCD1 | |
| SCHEMBL8075087 | 0.87 | DCLRE1B (0.51) | DCLRE1BFFAR1PTGS2 | |
| SCHEMBL8073879 | 0.87 | DCLRE1B (0.51) | DCLRE1BFFAR1PTGS2 | |
| SCHEMBL8073803 | 0.85 | SLC1A3 (0.39) | DCLRE1BAKR1C3AKR1C2PTGS2SLC1A3 | |
| SCHEMBL8078295 | 0.85 | SLC1A3 (0.39) | DCLRE1BAKR1C3AKR1C2PTGS2SLC1A3 | |
| SCHEMBL8075538 | 0.84 | DCLRE1B (0.39) | DCLRE1BPTGS2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8064541 | 0.84 | DCLRE1B (0.39) | DCLRE1BPTGS2SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8075742 | 0.83 | DCLRE1B (0.40) | DCLRE1BFFAR1PTGS2ITGB2ICAM1 | |
| SCHEMBL8079616 | 0.82 | MEN1 (0.42) | TTRAKR1C3AKR1C2PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | claimed |
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |