Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTSV | O60911 | 3/20 | 0.43 |
| ▸ | CTSL | P07711 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 3/20 | 0.43 |
| ▸ | CTSK | P43235 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9318523 | 0.81 | ALOX5 (0.42) | PPARGPPARAMAPTKMT2ALMNA | |
| SCHEMBL9319910 | 0.80 | GRM5 (0.42) | PPARGPPARACTSVCTSLCTSB | |
| SCHEMBL9319482 | 0.79 | CYP3A4 (0.47) | GAAMAPTKMT2ALMNAALOX5 | |
| SCHEMBL9318605 | 0.79 | ALOX5 (0.45) | ALOX5MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2428821 | 0.78 | MDM2 (0.51) | PPARGPPARACTSVCTSLCTSB | |
| SCHEMBL12983883 | 0.77 | NPC1 (0.49) | GAAMAPTKMT2ALMNASMN1; SMN2 | |
| SCHEMBL8985598 | 0.76 | MMP8 (0.43) | GAAKMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL9318888 | 0.76 | MMP8 (0.43) | GAAKMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL19945770 | 0.76 | MMP8 (0.50) | PPARGGAAMAPTKMT2ALMNA | |
| SCHEMBL19945772 | 0.76 | MMP8 (0.50) | PPARGGAAMAPTKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6060462-A | Electrophilic peptide analogs as inhibitors of trypsin-like enzymes | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-05-09 | — | — | US | disclosed |