Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 5/20 | 0.51 |
| ▸ | LDHB | P07195 | 5/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.49 |
| ▸ | DHODH | Q02127 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | ATIC | P31939 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31520079 | 1.00 | LDHA (0.51) | LDHALDHBPDE10ADHODHTSHR | |
| SCHEMBL5162563 | 0.86 | PDE10A (0.50) | LDHALDHBPDE10ADHODHTSHR | |
| SCHEMBL5160775 | 0.84 | PDE10A (0.49) | LDHALDHBPDE10ADHODHTSHR | |
| SCHEMBL340400 | 0.84 | LDHA (0.51) | LDHALDHBPDE10ADHODHTSHR | |
| SCHEMBL19203141 | 0.84 | LDHA (0.49) | LDHALDHBPDE10ADHODHTSHR | |
| SCHEMBL30706629 | 0.84 | LDHA (0.49) | LDHALDHBPDE10ADHODHTSHR | |
| SCHEMBL19203138 | 0.84 | LDHA (0.66) | LDHALDHBPDE10ADHODHTSHR | |
| SCHEMBL28261469 | 0.83 | DHODH (0.52) | LDHALDHBPDE10ADHODHTSHR | |
| SCHEMBL29260803 | 0.83 | DHODH (0.55) | LDHALDHBPDE10ADHODHTSHR | |
| SCHEMBL31039922 | 0.81 | DHODH (0.50) | LDHALDHBPDE10ADHODHTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6149841-A | COMPOUNDS SUCH AS 3,3-BIS(4-METHOXYPHENYL)-13-OXO-3,13-DIHYDROBENZO(B)PYRANO -(4',3':6,7)NAPHTHO(2,1-B)PYRAN; ACCEPTABLE FADE RATE WITHOUT THE ADDITION OF ACIDS OR BASES AND AN ACCEPTABLE COLORATION RATE AT ROOM TEMPERATURE | PPG INDUSTRIES OHIO, INC. (US) | 2000-11-21 | — | — | US | disclosed |