SCHEMBL8074243

SCHEMBL8074243

CC(C)C[C@H](N)C(=O)N(CC(=O)O)c1ccccc1

nearest known ligand 0.60

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR88 Q9GZN0 1/20 0.44
MLYCD O95822 1/20 0.44
LARS1 Q9P2J5 1/20 0.43
ANPEP P15144 1/20 0.43
RNPEP Q9H4A4 1/20 0.43
DNPEP Q9ULA0 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8074241 1.00 GPR88 (0.44) GPR88MLYCDLARS1ANPEPRNPEP
Hydrochloric Acid SCHEMBL5967108 0.85 MLYCD (0.45) GPR88MLYCDLARS1ANPEPRNPEP
SCHEMBL6303083 0.84 ALDH1A1 (0.47) MLYCD
SCHEMBL28110901 0.84 MLYCD (0.46) MLYCD
SCHEMBL14690329 0.84 MLYCD (0.48) MLYCD
SCHEMBL6047685 0.84 MLYCD (0.48) MLYCD
SCHEMBL5493790 0.83 MLYCD (0.45) MLYCD
SCHEMBL27459998 0.83 ACE (0.41) MLYCD
SCHEMBL1562840 0.83 ACE (0.41) MLYCD
Hydrochloric Acid SCHEMBL10509889 0.81 ACE (0.40) MLYCD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1038533-A1 MEDICINAL COMPOSITIONS FOR TREATING IMMUNODEFICIENCY DISEASES Nippon Kayaku Kabushiki Kaisha (JP) 2000-09-27 EP disclosed
EP-0347820-B1 NOVEL SPERGUALIN-RELATED COMPOUNDS AND PREPARATION AND APPLICATION OF THE SAME NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1993-04-21 EP disclosed
US-5061787-A IMMUNOSUPPRESSANTS NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1991-10-29 US disclosed
EP-0241797-B1 NOVEL SPERGUALIN-RELATED COMPOUNDS AND PROCESS FOR PRODUCING THE SAME MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1991-06-12 EP disclosed
US-4956504-A IMMUNOMODULATORS, ANTIBIOTICS ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JP) 1990-09-11 US disclosed
EP-0347820-A1 Novel spergualin-related compounds and preparation and application of the same NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1989-12-27 EP disclosed
EP-0241797-A2 Novel spergualin-related compounds and process for producing the same MICROBIAL CHEMISTRY RESEARCH FOUNDATION (JP) 1987-10-21 EP disclosed