Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PRKCA | P17252 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7196895 | 0.84 | TDP1 (0.46) | TDP1USP2ALDH1A1CYP3A4MAPT | |
| Triacetin SCHEMBL821340 | 0.83 | TDP1 (0.56) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8074473 | 0.83 | ALDH1A1 (0.58) | TDP1USP2ALDH1A1CYP3A4MAPT | |
| Triacetin SCHEMBL3870 | 0.83 | TDP1 (0.56) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL17707870 | 0.82 | PRKCA (0.53) | TDP1PRKCA | |
| Triacetin SCHEMBL7194199 | 0.82 | PRKCA (0.45) | TDP1USP2ALDH1A1CYP3A4MAPT | |
| SCHEMBL7215172 | 0.82 | ADRB2 (0.53) | TDP1ALDH1A1MEN1KMT2APRKCA | |
| SCHEMBL7257559 | 0.82 | ADRB2 (0.53) | TDP1ALDH1A1MEN1KMT2APRKCA | |
| Triacetin SCHEMBL16446056 | 0.81 | TDP1 (0.54) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A | |
| Triacetin SCHEMBL8012678 | 0.81 | TDP1 (0.54) | TDP1ALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133401-A1 | SYNTHESIS OF TIMOSAPONIN BII | PHYTOPHARM PLC (GB) | 2009-11-05 | — | — | WO | disclosed |