Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.33 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17460935 | 0.78 | ALDH1A1 (0.41) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL15082022 | 0.74 | GRIA2 (0.38) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL15081931 | 0.74 | GRIA2 (0.38) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL807448 | 0.70 | HTR2C (0.42) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL17460930 | 0.68 | HTR2A (0.43) | SLC6A3SLC6A2HTR2AHTR2CHTR2B | |
| SCHEMBL8391664 | 0.67 | HRH3 (0.49) | — | |
| SCHEMBL8393736 | 0.67 | HRH3 (0.49) | — | |
| SCHEMBL29098694 | 0.66 | ALDH1A1 (0.37) | HTR2AHTR2CHTR2BALDH1A1MEN1 | |
| SCHEMBL14544199 | 0.66 | DRD2 (0.49) | ALDH1A1 | |
| SCHEMBL28236085 | 0.65 | MAOA (0.39) | SLC6A3SLC6A2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036997-A1 | FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS | SCHERING CORPORATION (US) | 2012-03-22 | — | — | WO | disclosed |