Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.50 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.50 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.50 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL259581 | 0.88 | L3MBTL1 (0.59) | ALDH1A1MAPTHTTSMN1; SMN2HPGD | |
| SCHEMBL8079282 | 0.87 | GAA (0.50) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL5673080 | 0.84 | CNR2 (0.56) | ALDH1A1MAPTHTTSMN1; SMN2ATM | |
| SCHEMBL8079269 | 0.83 | CES2 (0.52) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL3406790 | 0.82 | LMNA (0.65) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL3038873 | 0.82 | CES2 (0.63) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL1258944 | 0.82 | CES2 (0.74) | SMN1; SMN2HPGDCES2CES1ABCC9 | |
| SCHEMBL25142152 | 0.81 | L3MBTL1 (0.52) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL15197219 | 0.81 | LMNA (0.50) | ALDH1A1MAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL28209093 | 0.81 | CES2 (0.49) | ALDH1A1MAPTHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |