Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 5/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070929 | 0.75 | CYP3A4 (0.47) | CHRNB2CHRNA4CA9CA12CYP3A4 | |
| SCHEMBL18682060 | 0.75 | CYP3A4 (0.47) | CHRNB2CHRNA4CA9CA12CYP3A4 | |
| SCHEMBL29636243 | 0.69 | CYP3A4 (0.48) | CHRNB2CHRNA4CA9CA12CYP3A4 | |
| SCHEMBL807465 | 0.69 | CYP3A4 (0.48) | CHRNB2CHRNA4CA9CA12CYP3A4 | |
| SCHEMBL29549133 | 0.69 | CYP3A4 (0.48) | CHRNB2CHRNA4CA9CA12CYP3A4 | |
| SCHEMBL23567922 | 0.69 | CYP3A4 (0.48) | CHRNB2CHRNA4CA9CA12CYP3A4 | |
| SCHEMBL372282 | 0.66 | ATM (0.58) | ATMCA9CA12CYP3A4ALDH1A1 | |
| SCHEMBL17789217 | 0.64 | ACHE (0.46) | CHRNB2CHRNA4ATMCYP3A4ALDH1A1 | |
| Hydrochloric Acid SCHEMBL14890696 | 0.64 | ATM (0.56) | ATMCA9CA12CYP3A4ALDH1A1 | |
| SCHEMBL22080750 | 0.63 | CA12 (0.41) | CHRNB2CHRNA4ATMCA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012035327-A1 | POLYMERISATION METHOD | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2012-03-22 | — | — | WO | disclosed |