Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004368 | 0.93 | TRPV1 (0.41) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8004374 | 0.93 | TRPV1 (0.41) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7988986 | 0.91 | MAOB (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL8004050 | 0.89 | MAOB (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL7999664 | 0.88 | MAOB (0.36) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL7998987 | 0.87 | ADRA2A (0.38) | ALDH1A1SMN1; SMN2MEN1KMT2AMAOB | |
| SCHEMBL8000955 | 0.85 | BACE1 (0.42) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL8000960 | 0.85 | BACE1 (0.42) | KDM4EALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL7992032 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL8004758 | 0.84 | ALOX15 (0.39) | KDM4EALDH1A1MEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| US-5942521-A | Quinolinone derivative and anti-allergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1999-08-24 | — | — | US | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |