Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CTSB | P07858 | 2/20 | 0.37 |
| ▸ | CTSS | P25774 | 2/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2627371 | 0.65 | SYK (0.74) | SYKCTSBCTSSCTSLMAPT | |
| SCHEMBL6312582 | 0.65 | SYK (0.74) | SYKCTSBCTSSCTSLMAPT | |
| SCHEMBL6312567 | 0.65 | SYK (0.74) | SYKCTSBCTSSCTSLMAPT | |
| SCHEMBL30460045 | 0.64 | SYK (0.72) | SYKCTSBCTSSCTSLCTSK | |
| SCHEMBL7433848 | 0.64 | SYK (0.56) | SYKNTSR1L3MBTL1CTSBCTSS | |
| Acetone SCHEMBL7365925 | 0.63 | CTSB (0.53) | SYKCTSBCTSSCTSLCTSK | |
| SCHEMBL10347229 | 0.63 | SYK (0.58) | SYKNTSR1L3MBTL1CTSBCTSS | |
| SCHEMBL5557488 | 0.63 | CTSS (0.52) | SYKCTSBCTSSCTSLLMNA | |
| SCHEMBL2725000 | 0.63 | SYK (0.71) | SYKCTSBCTSSCTSLMAPT | |
| SCHEMBL2723154 | 0.63 | SYK (0.71) | SYKCTSBCTSSCTSLMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009026701-A1 | SIRTUIN INHIBITORS | METHYLGENE INC. (CA) | 2009-03-05 | — | — | WO | disclosed |