Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 6/20 | 0.45 |
| ▸ | CTSL | P07711 | 6/20 | 0.45 |
| ▸ | CTSK | P43235 | 5/20 | 0.43 |
| ▸ | CTSB | P07858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10347229 | 0.89 | SYK (0.58) | SYKCTSSCTSLCTSKCTSB | |
| SCHEMBL10445815 | 0.88 | CTSS (0.47) | SYKCTSSCTSLCTSKCTSB | |
| SCHEMBL7434135 | 0.86 | SYK (0.54) | SYKCTSSCTSLCTSKCTSB | |
| SCHEMBL7434857 | 0.85 | SYK (0.56) | SYKCTSSCTSLCTSKCTSB | |
| SCHEMBL10432161 | 0.82 | CTSK (0.48) | CTSSCTSLCTSKCTSBELANE | |
| SCHEMBL5704553 | 0.82 | CTSL (0.53) | CTSSCTSLCTSKCTSBELANE | |
| SCHEMBL7429348 | 0.81 | CTSS (0.52) | CTSSCTSLCTSKCTSBELANE | |
| SCHEMBL7399913 | 0.81 | CTSS (0.52) | CTSSCTSLCTSKCTSBELANE | |
| SCHEMBL7442495 | 0.81 | SYK (0.60) | SYKCTSSCTSLCTSKCTSB | |
| SCHEMBL10445390 | 0.80 | SYK (0.47) | SYKCTSSCTSLCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371179-A1 | Novel analogs of peptidase substrates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0368719-A2 | Novel analogs of peptidase substrates | MERRELL PHARMACEUTICALS INC. (US) | 1990-05-16 | — | — | EP | disclosed |
| EP-0362002-A1 | HIV protease inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-04-04 | — | — | EP | disclosed |
| EP-0275101-A2 | Novel peptidase inhibitors | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-07-20 | — | — | EP | disclosed |