Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | DHFR | P00374 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL920526 | 0.88 | MCL1 (0.56) | MCL1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8079401 | 0.82 | PTGER1 (0.49) | MCL1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13460593 | 0.77 | MAPT (0.54) | MCL1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8074756 | 0.76 | MCL1 (0.45) | MCL1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7461166 | 0.73 | IDO1 (0.41) | MCL1LMNAALDH1A1USP2MAPT | |
| SCHEMBL434572 | 0.73 | NOTUM (0.35) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL920301 | 0.73 | HPGD (0.48) | MCL1HTR1ALMNAALDH1A1MAPT | |
| SCHEMBL919555 | 0.73 | IDO1 (0.51) | MCL1HTR1AALDH1A1MAPTPKM | |
| SCHEMBL921903 | 0.73 | CDK4 (0.48) | MCL1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL11739704 | 0.73 | APP (0.44) | LMNAALDH1A1TP53GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |