Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079403 | 0.83 | MCL1 (0.53) | MCL1MAPTL3MBTL1TDP1PTGER1 | |
| SCHEMBL27707593 | 0.80 | PTPRC (0.51) | ALDH1A1L3MBTL1TDP1DHFR | |
| SCHEMBL921994 | 0.77 | MAOB (0.50) | LMNAPKMKDM4EHTTNPC1 | |
| SCHEMBL8074754 | 0.76 | MCL1 (0.51) | MCL1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL434573 | 0.76 | PTPRC (0.46) | ALDH1A1MAPTL3MBTL1NPC1ALOX5AP | |
| SCHEMBL28829313 | 0.72 | DPP4 (0.52) | PTGER1PTGER4PTGER3PTGER2ALOX5AP | |
| SCHEMBL920526 | 0.72 | MCL1 (0.56) | MCL1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13460593 | 0.71 | MAPT (0.54) | MCL1HTR1ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8115423 | 0.70 | PGR (0.38) | — | |
| SCHEMBL13722318 | 0.68 | IDO1 (0.44) | MCL1HTR1ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |