SCHEMBL920526

SCHEMBL920526

Fc1[c]cccc1OCc1ccccc1F

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.56
LMNA P02545 3/20 0.50
ALDH1A1 P00352 2/20 0.50
HTR1A P08908 2/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 2/20 0.50
SLC6A3 Q01959 1/20 0.50
USP2 O75604 1/20 0.50
IDO1 P14902 2/20 0.49
MAPT P10636 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
KDM4E B2RXH2 2/20 0.48
PKM P14618 2/20 0.48
ESR1 P03372 1/20 0.48
TP53 P04637 1/20 0.48
GAA P10253 1/20 0.48
THRB P10828 1/20 0.48
ALOX12 P18054 1/20 0.48
BLM P54132 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8074754 0.88 MCL1 (0.51) MCL1LMNAALDH1A1HTR1ASLC6A2
SCHEMBL921903 0.84 CDK4 (0.48) MCL1LMNAALDH1A1HTR1ASLC6A2
SCHEMBL919555 0.84 IDO1 (0.51) MCL1ALDH1A1HTR1AIDO1MAPT
SCHEMBL920301 0.84 HPGD (0.48) MCL1LMNAALDH1A1HTR1AIDO1
SCHEMBL921446 0.80 PLAU (0.48) MCL1ALDH1A1KMT2AKDM4EPKM
SCHEMBL3211927 0.79 MAPT (0.50) LMNAALDH1A1HTR1ASLC6A2SLC6A4
SCHEMBL3326060 0.76 IDO1 (0.48) MCL1LMNAALDH1A1HTR1ASLC6A2
SCHEMBL920470 0.76 ALDH1A1 (0.50) LMNAALDH1A1HTR1ASLC6A2SLC6A4
SCHEMBL921453 0.74 SYK (0.49) ALDH1A1HTR1AKDM4ESMN1; SMN2
SCHEMBL23005041 0.74 MCL1 (0.61) MCL1LMNAALDH1A1HTR1ASLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110201649-A1 AGRICULTURAL COMPOSITION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-18 US disclosed
EP-2345328-A1 COMPOSITION FOR AGRICULTURAL USE Sumitomo Chemical Company, Limited (JP) 2011-07-20 EP disclosed
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-01-13 US disclosed
EP-2248423-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS Sumitomo Chemical Company, Limited (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110009454-A1 COMPOSITION FOR AGRICULTURAL USE FOR CONTROLLING OR PREVENTING PLANT DISEASES CAUSED BY PLANT PATHOGENS WIZ, TST, NAT1 MCL1 4826/4885LMNA 4812/4885ALDH1A1 2743/4885
US-20110201649-A1 AGRICULTURAL COMPOSITION H1-0, H1-3, H1-2 MCL1 4656/4885LMNA 3681/4885ALDH1A1 4326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.