Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14762676 | 0.95 | FFAR3 (0.36) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Hydrochloric Acid SCHEMBL8072773 | 0.79 | FDPS (0.34) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL459604 | 0.73 | — | — | |
| SCHEMBL8072767 | 0.71 | FDPS (0.36) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Ammonia Solution, Strong SCHEMBL28340659 | 0.71 | FDPS (0.36) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL8065098 | 0.71 | — | — | |
| SCHEMBL6624472 | 0.71 | FDPS (0.36) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL6625318 | 0.68 | KCNN4 (0.33) | FDPSTSHR | |
| SCHEMBL21269463 | 0.67 | FFAR3 (0.41) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL9731654 | 0.67 | FFAR3 (0.41) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0840723-A1 | SALTS OF ALPHA-HYDROXY ALIPHATIC CARBOXYLIC ACIDS AND USES THEREOF AS A SOURCE OF METHIONINE FOR DIETARY SUPPLEMENTATION | ZINPRO CORPORATION (US) | 1998-05-13 | — | — | EP | claimed |
| US-5583243-A | NUTRITIONAL SUPPLEMENTS | ZINPRO CORPORATION (US) | 1996-12-10 | — | — | US | claimed |
| WO-1996036598-A1 | SALTS OF ALPHA-HYDROXY ALIPHATIC CARBOXYLIC ACIDS AND USES THEREOF AS A SOURCE OF METHIONINE FOR DIETARY SUPPLEMENTATION | ZINPRO CORPORATION (US) | 1996-11-21 | — | — | WO | claimed |
| EP-0840723-B1 | Salts of aliphatic alpha-hydroxy carboxylic acids and their preparation | ZINPRO CORP (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5583243-A | NUTRITIONAL SUPPLEMENTS | ZINPRO CORPORATION (US) | 1996-12-10 | — | — | US | disclosed |