Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.39 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | MC4R | P32245 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8059454 | 0.85 | HTR2A (0.38) | FFAR1LPAR1LPAR5SLC6A4HTR2A | |
| SCHEMBL8070159 | 0.84 | FFAR1 (0.42) | FFAR1LPAR1LPAR5SLC6A4SCN9A | |
| SCHEMBL8070202 | 0.83 | SCN9A (0.39) | FFAR1LPAR1LPAR5SLC6A4HTR2A | |
| SCHEMBL8068470 | 0.83 | — | — | |
| SCHEMBL8428714 | 0.75 | SLC9A1 (0.51) | SLC9A1KCNH2MC4R | |
| Hydrochloric Acid SCHEMBL8335179 | 0.74 | SLC9A1 (0.50) | SLC9A1KCNH2MC4R | |
| Hydrochloric Acid SCHEMBL8655510 | 0.72 | SLC9A1 (0.43) | SLC9A1KCNH2MC4R | |
| SCHEMBL7791856 | 0.72 | MRGPRX4 (0.48) | — | |
| SCHEMBL8075018 | 0.72 | SLC6A2 (0.43) | FFAR1LPAR1LPAR5SLC6A4SCN9A | |
| Hydrochloric Acid SCHEMBL8073478 | 0.71 | SLC9A1 (0.52) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |