Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.37 |
| ▸ | RET | P07949 | 1/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | RAF1 | P04049 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070202 | 0.84 | SCN9A (0.39) | FFAR1LPAR1LPAR5SCN9ALMNA | |
| SCHEMBL8075014 | 0.84 | FFAR1 (0.39) | FFAR1LPAR1LPAR5SCN9ATHRA | |
| SCHEMBL8070508 | 0.84 | LPAR1 (0.39) | FFAR1LPAR1LPAR5LMNAKMT2A | |
| SCHEMBL8068627 | 0.82 | LPAR1 (0.48) | FFAR1LPAR1LPAR5SCN9AMRGPRX4 | |
| SCHEMBL8068838 | 0.81 | ALDH1A1 (0.41) | FFAR1LPAR1LPAR5SCN9ALMNA | |
| SCHEMBL8333315 | 0.74 | GAA (0.49) | MRGPRX4LMNAKMT2AMEN1MAPT | |
| SCHEMBL7953912 | 0.71 | MRGPRX4 (0.56) | MRGPRX4LMNA | |
| SCHEMBL8074970 | 0.71 | SLC6A2 (0.45) | FFAR1LPAR1LPAR5SCN9ATHRA | |
| SCHEMBL8075018 | 0.71 | SLC6A2 (0.43) | FFAR1LPAR1LPAR5SCN9ATHRA | |
| Hydrochloric Acid SCHEMBL8070331 | 0.70 | SLC6A2 (0.44) | FFAR1LPAR1LPAR5SCN9ATHRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |