Sugi Predict

Sugi Predict / Compounds / SCHEMBL807502

SCHEMBL807502

SCHEMBL807502

CCC(CC)COC(=O)[C@H](C)N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 5/20 0.40
▸ TSHR P16473 3/20 0.40
▸ ATM Q13315 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ RECQL P46063 1/20 0.37
▸ ALDH1A1 P00352 3/20 0.35
▸ CA2 P00918 1/20 0.35
▸ GRIN2D O15399 1/20 0.35
▸ GRIN3B O60391 1/20 0.35
▸ GRIN1 Q05586 1/20 0.35
▸ GRIN2A Q12879 1/20 0.35
▸ GRIN2B Q13224 1/20 0.35
▸ GRIN2C Q14957 1/20 0.35
▸ GRIN3A Q8TCU5 1/20 0.35
▸ PRSS1 P07477 1/20 0.33
▸ PRSS2 P07478 1/20 0.33
▸ PRSS3 P35030 1/20 0.33
▸ ALOX15 P16050 1/20 0.32
▸ LMNA P02545 2/20 0.32
▸ CHRNB2 P17787 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25526434 1.00 CYP3A4 (0.40) CYP3A4TSHRATMTDP1RECQL
SCHEMBL14989535 1.00 CYP3A4 (0.40) CYP3A4TSHRATMTDP1RECQL
Hydrochloric Acid SCHEMBL1273080 0.98 CYP3A4 (0.39) CYP3A4TSHRATMTDP1RECQL
Hydrochloric Acid SCHEMBL16698594 0.98 CYP3A4 (0.39) CYP3A4TSHRATMTDP1RECQL
Hydrochloric Acid SCHEMBL28854892 0.98 CYP3A4 (0.39) CYP3A4TSHRATMTDP1RECQL
SCHEMBL27670822 0.85 CYP3A4 (0.62) CYP3A4TSHRATMTDP1RECQL
SCHEMBL22349621 0.85 CYP3A4 (0.62) CYP3A4TSHRATMTDP1RECQL
SCHEMBL30964178 0.83 CYP3A4 (0.60) CYP3A4TSHRATMTDP1RECQL
SCHEMBL8140144 0.83 CA2 (0.44) CYP3A4TSHRATMTDP1RECQL
SCHEMBL16113894 0.83 CA2 (0.44) CYP3A4TSHRATMTDP1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111269263-A Rudexilvir side chain intermediate and preparation method thereof 上海龙翔生物医药开发有限公司 2020-06-12 — — CN claimed
US-20260035394-A1 1`-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF GILEAD SCIENCES INC (US) 2026-02-05 — — US disclosed
US-12404289-B2 1′-cyano nucleoside analogs and uses thereof GILEAD SCIENCES, INC. (US) 2025-09-02 — — US disclosed
CN-108348526-B Methods of treating arenaviridae and coronaviridae viral infections 吉利德科学公司 2025-04-25 — — CN disclosed
CN-113493480-B Preparation and analysis method of Ruidexivir isomer 南京正大天晴制药有限公司 2025-04-15 — — CN disclosed
CN-115175735-B Antiviral compounds 吉利德科学公司 2025-03-04 — — CN disclosed
CN-119403815-A Didehydro-3 '-deoxy-4' -ethynyl thymidine and related compounds and their use in treating medical conditions 罗梅治疗股份有限公司 2025-02-07 — — CN disclosed
CN-112513061-B 4' -Thio-nucleotides and-nucleoside prodrugs for treating cancer 南方研究院 2025-01-24 — — CN disclosed
CN-118994170-A Process for preparing 1' -cyanonucleosides 吉利德科学公司 2024-11-22 — — CN disclosed
CN-118619991-A Phosphoramidate prodrug, preparation method and medical application thereof 中国药科大学 2024-09-10 — — CN disclosed
US-20130143835-A1 HCV Polymerase Inhibitors MEDIVIR AB (SE) 2013-06-06 — — US disclosed
US-20130143835-A1 HCV Polymerase Inhibitors MEDIVIR AB (SE) 2013-06-06 — — US disclosed
US-20130143835-A1 HCV Polymerase Inhibitors MEDIVIR AB (SE) 2013-06-06 — — US disclosed
CN-103052631-A Methods and compounds for treating paramyxoviridae virus infections GILEAD SCIENCES INC 2013-04-17 — — CN disclosed
US-20120107274-A1 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2012-05-03 — — US disclosed
US-20120107274-A1 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2012-05-03 — — US disclosed
WO-2012037038-A1 2' -FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT GILEAD SCIENCES, INC. (US) 2012-03-22 — — WO disclosed
US-20120027752-A1 METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. (US) 2012-02-02 — — US disclosed
US-20120027752-A1 METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. (US) 2012-02-02 — — US disclosed
WO-2012012776-A1 METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. (US) 2012-01-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120107274-A1 2'-FLUORO SUBSTITUTED CARBA-NUCLEOSIDE ANALOGS FOR ANTIVIRAL TREATMENT PNP, NUDT1, SLC29A2 CYP3A4 1139/4885TSHR 816/4885ATM 3645/4885
US-20120027752-A1 METHODS AND COMPOUNDS FOR TREATING PARAMYXOVIRIDAE VIRUS INFECTIONS PNP, RPIA, HPRT1 CYP3A4 1697/4885TSHR 3767/4885ATM 2749/4885
US-20130143835-A1 HCV Polymerase Inhibitors POLI, HAVCR2, EIF2AK2 CYP3A4 557/4885TSHR 4393/4885ATM 4448/4885
US-12404289-B2 1′-cyano nucleoside analogs and uses thereof TYMP, PNP, DUT CYP3A4 2012/4885TSHR 4765/4885ATM 3726/4885
US-20260035394-A1 1`-CYANO NUCLEOSIDE ANALOGS AND USES THEREOF PNP, SLC28A1, SLC29A1 CYP3A4 1360/4885TSHR 4134/4885ATM 3054/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.