Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 2/20 | 0.40 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 3/20 | 0.38 |
| ▸ | MMP3 | P08254 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079610 | 0.84 | MMP2 (0.49) | ACEMMP2MMP3MME | |
| SCHEMBL8064698 | 0.84 | MEN1 (0.42) | ACECA1CA2MEN1PTGS1 | |
| SCHEMBL8079616 | 0.84 | MEN1 (0.42) | ACECA1CA2MEN1PTGS1 | |
| SCHEMBL9221137 | 0.79 | RARB (0.50) | RARBFDFT1CA1CA2MEN1 | |
| SCHEMBL8990699 | 0.78 | RARB (0.49) | RARBFDFT1CA1CA2MEN1 | |
| SCHEMBL8066034 | 0.77 | ACE (0.45) | ACEMMP2MEN1KMT2ALMNA | |
| SCHEMBL8080452 | 0.77 | ACE (0.45) | ACEMMP2MEN1KMT2ALMNA | |
| SCHEMBL8073254 | 0.76 | ACE (0.45) | ACEMMP2MMP3PTGS2KDM4E | |
| SCHEMBL8726493 | 0.76 | RARB (0.48) | RARBFDFT1CA1CA2MEN1 | |
| SCHEMBL8080420 | 0.76 | SLC6A4 (0.46) | ACEMMP2MMP3KMT2APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |