Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.45 |
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | BAD | Q92934 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 2/20 | 0.42 |
| ▸ | MMP13 | P45452 | 2/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080452 | 0.91 | ACE (0.45) | ACEMMEMMP2MMP9MAPT | |
| SCHEMBL8066034 | 0.91 | ACE (0.45) | ACEMMEMMP2MMP9MAPT | |
| SCHEMBL8080420 | 0.90 | SLC6A4 (0.46) | ACEMMECACNA1BMMP1MMP2 | |
| SCHEMBL8064541 | 0.88 | DCLRE1B (0.39) | ACEMMECACNA1BMMP1MMP2 | |
| SCHEMBL8075538 | 0.88 | DCLRE1B (0.39) | ACEMMECACNA1BMMP1MMP2 | |
| SCHEMBL8075762 | 0.85 | ACE (0.44) | ACEMMEMMP1MMP2MMP3 | |
| SCHEMBL8073434 | 0.83 | ACE (0.45) | ACEMMEMMP1MMP2MMP3 | |
| SCHEMBL30118364 | 0.82 | ALDH1A1 (0.52) | ACEMMECPA1ACE2 | |
| SCHEMBL8075736 | 0.80 | GPR34 (0.45) | ACEMMEMMP1MMP2MMP3 | |
| SCHEMBL110457 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |