Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 5/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.41 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066034 | 1.00 | ACE (0.45) | ACELMNAALDH1A1MAPTMEN1 | |
| SCHEMBL8073254 | 0.91 | ACE (0.45) | ACEMAPTMMEACE2CPA1 | |
| SCHEMBL8075736 | 0.89 | GPR34 (0.45) | ACEMMEGPR34MMP2MMP9 | |
| SCHEMBL8064541 | 0.85 | DCLRE1B (0.39) | ACEMMEACE2CPA1GPR34 | |
| SCHEMBL8075538 | 0.85 | DCLRE1B (0.39) | ACEMMEACE2CPA1GPR34 | |
| SCHEMBL8080420 | 0.82 | SLC6A4 (0.46) | ACELMNAALDH1A1MAPTKMT2A | |
| SCHEMBL30118364 | 0.81 | ALDH1A1 (0.52) | ACEALDH1A1MMEACE2CPA1 | |
| SCHEMBL8079610 | 0.79 | MMP2 (0.49) | ACEMMEGPR34MMP2MMP9 | |
| SCHEMBL8075762 | 0.77 | ACE (0.44) | ACEMAPTMEN1KMT2AMME | |
| SCHEMBL8075290 | 0.77 | RARB (0.46) | ACELMNAALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | claimed |
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |