SCHEMBL8075355

SCHEMBL8075355

FC(F)(F)c1ccc2c(c1)C1C(=Cc3ccccc31)[Si](Cc1ccccc1)(Cc1ccccc1)C1=Cc3ccccc3C1c1cc(C(F)(F)F)ccc1O[Zr]O2

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
MRGPRX4 Q96LA9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8082812 0.84 CYP1A2 (0.35) CYP1A2CYP2D6
SCHEMBL5608741 0.79 CYP1A2 (0.34) CYP1A2CYP2D6MRGPRX4
SCHEMBL8086807 0.76 CYP1A2 (0.36) CYP1A2CYP2D6
SCHEMBL5496103 0.69 PPARG (0.34) CYP1A2CYP2D6MRGPRX4
SCHEMBL6684067 0.65 KMT2A (0.35)
SCHEMBL8083522 0.59 TERT (0.33)
SCHEMBL8075360 0.59 PNMT (0.32)
SCHEMBL5081353 0.58 MEN1 (0.32)
SCHEMBL11835829 0.55 P2RX4 (0.44) CYP1A2CYP2D6
SCHEMBL17141529 0.55 MRGPRX4 (0.72) MRGPRX4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1041084-A1 SOLID CATALYST FOR OLEFIN POLYMERIZATION AND PROCESS FOR PRODUCING OLEFIN POLYMER WITH THE SAME MARUZEN PETROCHEMICAL CO., LTD. (JP) 2000-10-04 EP disclosed