Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 3/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8080550 | 0.92 | THRB (0.45) | MAPTTHRBTSHRHPGDALDH1A1 | |
| SCHEMBL8077109 | 0.89 | PPARG (0.42) | MAPTTHRBTSHRHPGDALDH1A1 | |
| SCHEMBL8077449 | 0.89 | MAPT (0.43) | MAPTTHRBTSHRHPGDALDH1A1 | |
| SCHEMBL8075506 | 0.89 | CSF1R (0.39) | MAPTTHRBTSHRHPGDALDH1A1 | |
| SCHEMBL8080543 | 0.86 | MAPT (0.44) | MAPTTHRBTSHRHPGDALDH1A1 | |
| SCHEMBL8077181 | 0.85 | HDAC1 (0.44) | MAPTTHRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL8076445 | 0.85 | HDAC1 (0.44) | MAPTTHRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL8082015 | 0.85 | HDAC1 (0.44) | MAPTTHRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL8082122 | 0.85 | HDAC1 (0.44) | MAPTTHRBTSHRALDH1A1CYP3A4 | |
| SCHEMBL8082135 | 0.85 | HDAC1 (0.44) | MAPTTHRBTSHRALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0755918-B1 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | ROLIC AG (CH) | 2000-09-06 | — | — | EP | disclosed |
| EP-0755918-A2 | Photocrosslinkable liquid crystalline 1,2-phenylene derivatives | Rolic AG (CH) | 1997-01-29 | — | — | EP | disclosed |