SCHEMBL8075508

SCHEMBL8075508

CC(C)c1c(Cl)cc(N)c(O)c1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.39
GABRB1 P18505 1/20 0.39
GAA P10253 5/20 0.39
THRB P10828 1/20 0.38
CD44 P16070 1/20 0.37
MMP14 P50281 1/20 0.36
HSD17B10 Q99714 4/20 0.36
HPGD P15428 3/20 0.36
TSHR P16473 2/20 0.36
CASP1 P29466 1/20 0.36
ALDH1A1 P00352 5/20 0.35
ALOX12 P18054 2/20 0.35
HIF1A Q16665 2/20 0.35
HTT P42858 1/20 0.35
LMNA P02545 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
KDM4E B2RXH2 1/20 0.34
MAPT P10636 1/20 0.34
CA12 O43570 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8088986 0.98 GABRA1 (0.38) GABRA1GABRB1GAATHRBCD44
SCHEMBL8075674 0.81 GAA (0.46) GABRA1GABRB1GAATHRBCD44
Hydrochloric Acid SCHEMBL8087141 0.80 GAA (0.45) GAATHRBCD44MMP14HSD17B10
SCHEMBL23079373 0.78 GABRA1 (0.41) GABRA1GABRB1HSD17B10HPGDTSHR
SCHEMBL18262814 0.77 LMNA (0.44) GABRA1GABRB1GAATHRBHSD17B10
SCHEMBL11155205 0.75 HSD17B10 (0.59) GAATHRBCD44MMP14HSD17B10
SCHEMBL31532309 0.74 CD44 (0.44) GAATHRBCD44MMP14HSD17B10
SCHEMBL2527588 0.74 CD44 (0.44) GAATHRBCD44MMP14HSD17B10
SCHEMBL8437999 0.73 FABP3 (0.38) GABRA1GABRB1MMP14HSD17B10HPGD
Hydrochloric Acid SCHEMBL3843541 0.72 ALDH1A1 (0.44) GAATHRBCD44MMP14HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0608896-B2 Process for producing aromatic amide compounds useful as cyan coupler for color photographs SUMITOMO CHEMICAL CO (JP) 2000-11-02 EP disclosed
US-5442114-A Process for producing aromatic amide compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-08-15 US disclosed
EP-0608896-A1 Process for producing aromatic amide compounds useful as cyan coupler for color photographes SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-08-03 EP disclosed
EP-0175151-B1 2,4-DICHLORO-3-ALKYL-6-NITROPHENOLS AND PROCESS FOR THEIR PREPARATION BAYER AG (DE) 1989-01-18 EP disclosed
US-4670608-A CATALYTIC CHLORINATION OF 1-ALKYL-4-NITROBENZENE BAYER AKTIENGESELLSCHAFT (DE) 1987-06-02 US disclosed
EP-0175151-A1 2,4-Dichloro-3-alkyl-6-nitrophenols and process for their preparation BAYER AG (DE) 1986-03-26 EP disclosed