SCHEMBL8075739

SCHEMBL8075739

CCOc1ccc(C=CC(=O)OCCC(C)C)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.76
TDP1 Q9NUW8 1/20 0.76
TAS1R3 Q7RTX0 2/20 0.55
TAS1R1 Q7RTX1 2/20 0.55
NPC1 O15118 3/20 0.52
RAB9A P51151 3/20 0.52
MAPT P10636 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
HTT P42858 1/20 0.52
KMT2A Q03164 1/20 0.52
SLC5A1 P13866 1/20 0.52
SLC5A2 P31639 1/20 0.52
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
CA7 P43166 1/20 0.51
CA9 Q16790 1/20 0.51
CA14 Q9ULX7 1/20 0.51
MAOB P27338 9/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22400703 1.00 LMNA (0.76) LMNATDP1TAS1R3TAS1R1NPC1
Amiloxate SCHEMBL15764 0.86 LMNA (1.00) LMNATDP1TAS1R3TAS1R1RAB9A
Amiloxate SCHEMBL2228053 0.86 LMNA (1.00) LMNATDP1TAS1R3TAS1R1RAB9A
Amiloxate SCHEMBL2228049 0.86 LMNA (1.00) LMNATDP1TAS1R3TAS1R1RAB9A
Amiloxate SCHEMBL15765 0.86 LMNA (1.00) LMNATDP1TAS1R3TAS1R1RAB9A
Amiloxate SCHEMBL8095776 0.86 LMNA (1.00) LMNATDP1TAS1R3TAS1R1RAB9A
SCHEMBL19244431 0.86 APP (0.61) LMNATDP1NPC1RAB9AMAPT
SCHEMBL19244429 0.86 APP (0.61) LMNATDP1NPC1RAB9AMAPT
Amiloxate SCHEMBL31304727 0.85 LMNA (0.97) LMNATDP1TAS1R3TAS1R1RAB9A
SCHEMBL14339508 0.85 APP (0.64) LMNATDP1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5985292-A COSMETIC OR DERMATOLOGICAL COMPOSITIONS OF THE INVENTION FOR THE TREATMENT AND CARE OF SKIN ROUSSEL-UCLAF (FR) 1999-11-16 US claimed
US-11585750-B2 Arrangement for determining body surface properties by means of Multiple Spatially Resolved Reflection Spectroscopy (MSRRS) HENKEL AG & CO. KGAA (DE) 2023-02-21 US disclosed
US-20200300754-A1 ARRANGEMENT FOR DETERMINING BODY SURFACE PROPERTIES BY MEANS OF MULTIPLE SPATIALLY RESOLVED REFLECTION SPECTROSCOPY (MSRRS) HENKEL AG & CO. KGAA (DE) 2020-09-24 US disclosed
EP-3707725-A1 ARRANGEMENT FOR DETERMINING BODY SURFACE PROPERTIES BY MEANS OF MULTIPLE SPATIALLY RESOLVED REFLECTION SPECTROSCOPY (MSRRS) Henkel AG & Co. KGaA (DE) 2020-09-16 EP disclosed
US-6133463-A FOR USE IN COSMETIC AND DERMATOLOGICAL COMPOSITIONS FOR TREATING OR CARING FOR THE SKIN THE BOOTS COMPANY PLC. (GB) 2000-10-17 US disclosed
US-5985292-A COSMETIC OR DERMATOLOGICAL COMPOSITIONS OF THE INVENTION FOR THE TREATMENT AND CARE OF SKIN ROUSSEL-UCLAF (FR) 1999-11-16 US disclosed
US-5656278-A SKIN PROTECTIVE CREAM COMPRISING A MIXTURE OF A CERAMIDE AND A LINOLEIC ACID VEGETABLE OIL THE BOOTS COMPANY PLC (GB) 1997-08-12 US disclosed
EP-0646370-B1 Cosmetic and dermatological compositions containing an association of ceramides and linoleic acids, their preparation ROUSSEL UCLAF (FR) 1996-07-24 EP disclosed
EP-0659755-A1 Phospholipids as vectors for active molecules, their preparation and their use in cosmetic or dermatologic compositions ROUSSEL UCLAF (FR) 1995-06-28 EP disclosed
EP-0646370-A1 Cosmetic and dermatological compositions containing an association of ceramides and linoleic acids, their preparation ROUSSEL UCLAF (FR) 1995-04-05 EP disclosed