SCHEMBL8075862

SCHEMBL8075862

NOCC(O)C(O)C(O)C(O)C(O)CO

nearest known ligand 0.60

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.60
LMNA P02545 2/20 0.55
L3MBTL1 Q9Y468 1/20 0.55
USP2 O75604 1/20 0.41
SLCO1B1 Q9Y6L6 1/20 0.41
KDM4E B2RXH2 2/20 0.39
PDE4A P27815 1/20 0.39
MGAM O43451 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6542053 1.00 TDP1 (0.60) TDP1LMNAL3MBTL1USP2SLCO1B1
SCHEMBL11423256 1.00 TDP1 (0.60) TDP1LMNAL3MBTL1USP2SLCO1B1
SCHEMBL1671960 0.97 LMNA (0.58) TDP1LMNAL3MBTL1USP2SLCO1B1
SCHEMBL5032170 0.97 LMNA (0.58) TDP1LMNAL3MBTL1USP2SLCO1B1
Mannitol SCHEMBL4971188 0.97 LMNA (0.58) TDP1LMNAL3MBTL1USP2SLCO1B1
SCHEMBL1129672 0.97 LMNA (0.58) TDP1LMNAL3MBTL1USP2SLCO1B1
SCHEMBL6541711 0.92 LMNA (0.50) TDP1LMNAL3MBTL1USP2SLCO1B1
SCHEMBL15892815 0.91 LMNA (0.50) TDP1LMNAL3MBTL1USP2SLCO1B1
SCHEMBL14654998 0.87 LMNA (0.37) TDP1LMNAL3MBTL1
Succinic Acid SCHEMBL5075718 0.83 USP2 (0.47) TDP1LMNAL3MBTL1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0830208-B1 METHOD OF DEPRESSING NON-SULFIDE SILICATE GANGUE MINERALS CYTEC TECH CORP (US) 2000-07-26 EP disclosed
EP-0830209-B1 METHOD OF DEPRESSING NON-SULFIDE SILICATE GANGUE MINERALS CYTEC TECH CORP (US) 1999-08-11 EP disclosed
EP-0830209-A1 METHOD OF DEPRESSING NON-SULFIDE SILICATE GANGUE MINERALS CYTEC TECHNOLOGY CORP. (US) 1998-03-25 EP disclosed
EP-0830208-A1 METHOD OF DEPRESSING NON-SULFIDE SILICATE GANGUE MINERALS Cytec Technology Corp. (US) 1998-03-25 EP disclosed
WO-1996040439-A1 METHOD OF DEPRESSING NON-SULFIDE SILICATE GANGUE MINERALS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO disclosed
WO-1996040438-A1 METHOD OF DEPRESSING NON-SULFIDE SILICATE GANGUE MINERALS CYTEC TECHNOLOGY CORP. (US) 1996-12-19 WO disclosed
US-5533626-A FROTH FLOTATION USING POLYMER MIXTURE OF POLYSACCHARIDES ANDACRYLAMIDE POLYMER CYTEC TECHNOLOGY CORP. (US) 1996-07-09 US disclosed
US-5525212-A USING MIXTURE OF A POLYSACCHARIDE AND A GRAFT POLYMER OF VINYL ALCOHOL AND ACRYLAMIDE CYTEC TECHNOLOGY CORP. (US) 1996-06-11 US disclosed
US-5507395-A IMPROVING FROTH FLOTATION WITH A DEPRESSANT COMPRISING A GRAFT POLYMER OF VINYL ALCOHOL AND AN ACRYLAMIDES CYTEC TECHNOLOGY CORP. (US) 1996-04-16 US disclosed
US-4720339-A Flotation beneficiation process for non-sulfide minerals AMERICAN CYANAMID COMPANY (US) 1988-01-19 US disclosed