Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | EP300 | Q09472 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835056 | 0.77 | KDM4E (0.65) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9259012 | 0.76 | KDM4E (0.53) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL16655565 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1523070 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3582572 | 0.73 | KDM4E (0.57) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1408375 | 0.72 | SMN1; SMN2 (0.56) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9535544 | 0.72 | KDM4E (1.00) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL2266248 | 0.72 | KDM4E (0.57) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11544557 | 0.72 | MAPT (0.59) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11828702 | 0.71 | KDM4E (0.55) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0785190-B1 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK & CHEMICALS (JP) | 2000-08-16 | — | — | EP | disclosed |
| EP-0785190-A2 | Quinolinone derivative and antiallergic agent with said quinolinone derivative as the active ingredient | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1997-07-23 | — | — | EP | disclosed |