Sugi Predict

Sugi Predict / Compounds / SCHEMBL835056

SCHEMBL835056

SCHEMBL835056

Cn1c(=O)cc(O)c2ccccc21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 0.65
▸ NQO2 P16083 1/20 0.65
▸ ALDH1A1 P00352 7/20 0.59
▸ HSD17B10 Q99714 4/20 0.59
▸ MAPT P10636 4/20 0.58
▸ HPGD P15428 3/20 0.58
▸ THRB P10828 1/20 0.58
▸ NPSR1 Q6W5P4 1/20 0.58
▸ KMT2A Q03164 3/20 0.54
▸ MEN1 O00255 2/20 0.54
▸ SMN1; SMN2 Q16637 2/20 0.54
▸ HTT P42858 2/20 0.53
▸ CYP2C19 P33261 2/20 0.51
▸ GLA P06280 1/20 0.51
▸ GAA P10253 1/20 0.51
▸ GPR3 P46089 1/20 0.50
▸ KCNA3 P22001 1/20 0.49
▸ ERCC1 P07992 1/20 0.49
▸ FEN1 P39748 1/20 0.49
▸ ERCC4 Q92889 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27910155 0.81 KDM4E (0.48) KDM4ENQO2ALDH1A1HSD17B10MAPT
SCHEMBL436564 0.78 KDM4E (1.00) KDM4ENQO2ALDH1A1HSD17B10MAPT
SCHEMBL19719694 0.78 KDM4E (0.61) KDM4ENQO2ALDH1A1HSD17B10MAPT
SCHEMBL2266978 0.78 KDM4E (0.51) KDM4ENQO2ALDH1A1HSD17B10MAPT
SCHEMBL7462175 0.78 ALDH1A1 (0.83) KDM4EALDH1A1HSD17B10MAPTHPGD
SCHEMBL1523070 0.77 KDM4E (0.57) KDM4ENQO2ALDH1A1HSD17B10MAPT
SCHEMBL9385739 0.77 MAPT (0.53) KDM4ENQO2ALDH1A1HSD17B10MAPT
SCHEMBL16655565 0.77 KDM4E (0.57) KDM4ENQO2ALDH1A1HSD17B10MAPT
SCHEMBL3582572 0.77 KDM4E (0.57) KDM4ENQO2ALDH1A1HSD17B10MAPT
SCHEMBL30557144 0.77 KDM4E (0.65) KDM4ENQO2ALDH1A1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115011576-B Aquilaria sinensis-derived III-type polyketide synthase AsPKS, and encoding gene and application thereof 中国医学科学院药用植物研究所 2024-10-25 — — CN claimed
CN-115161300-B Aquilaria sinensis-derived III-type polyketide synthase AsPKS, and encoding gene and application thereof 中国医学科学院药用植物研究所 2024-08-23 — — CN claimed
CN-114990084-B Aquilaria sinensis-derived III-type polyketide synthase AsPKS4, and encoding gene and application thereof 中国医学科学院药用植物研究所 2024-08-23 — — CN claimed
US-6852734-B2 Indole derivatives exhibiting chymase-inhibitory activities and process for preparation thereof MEIJI SEIKA KAISHA, LTD. (JP) 2005-02-08 — — US claimed
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses L'OREAL (FR) 2004-11-25 — — US claimed
EP-1428510-A1 Dyeing composition comprising a tertiary paraphenylenediamine containing a pyrrolidine, and a heterocyclic coupler or a hydroxybenzamide ; method and use L'OREAL (FR) 2004-06-16 — — EP claimed
US-20040058963-A1 Novel indole derivatives exhibiting chymase-inhibitory activities and process for preparation thereof MEIJI SEIKA KAISHA, LTD. (JP) 2004-03-25 — — US claimed
EP-1284266-A1 NOVEL INDOLE DERIVATIVES EXHIBITING CHYMASE-INHIBITORY ACTIVITIES AND PROCESS FOR PREPARATION THEREOF MEIJI SEIKA KAISHA LTD. (JP) 2003-02-19 — — EP claimed
EP-0142104-B1 FIBRE-REACTIVE CHROMIUM COMPLEXES, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1990-01-03 — — EP claimed
US-4723001-A Fibre-reactive chromium complexes and their preparation and use CIBA-GEIGY CORPORATION (US) 1988-02-02 — — US claimed
US-4159264-A Automatic control of azo coupling processes in the manufacture of azo pigments CIBA-GEIGY CORPORATION (US) 1979-06-26 — — US claimed
US-20250074925-A1 RARE EARTH COMPLEX SAGAMI CHEMICAL RESEARCH INSTITUTE (JP) 2025-03-06 — — US disclosed
CN-119371432-A Alpha-mangostin derivative and preparation method and application thereof 上海如凌生物医药有限公司 2025-01-28 — — CN disclosed
CN-115103841-B Substituted quinolinone piperazine compounds useful as T cell activators 百时美施贵宝公司 2024-12-27 — — CN disclosed
CN-115011576-B Aquilaria sinensis-derived III-type polyketide synthase AsPKS, and encoding gene and application thereof 中国医学科学院药用植物研究所 2024-10-25 — — CN disclosed
US-4032528-A DEPRESSANTS SANDOZ, INC. (US) 1977-06-28 — — US disclosed
US-4028323-A WITH A SUBSTITUTED AMINOBENZENE CIBA-GEIGY AG (CH) 1977-06-07 — — US disclosed
US-3971740-A DYES FOR POLYESTER FIBERS CIBA-GEIGY AG (CH) 1976-07-27 — — US disclosed
US-3968119-A OPTICAL BRIGHTENERS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-06 — — US disclosed
US-3945991-A Heterocyclic azo compounds containing a quaternated hydrazide group CIBA-GEIGY AG (CH) 1976-03-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074925-A1 RARE EARTH COMPLEX L1CAM, CHRM1, NPM1 KDM4E 4590/4885NQO2 150/4885ALDH1A1 2286/4885
US-20040058963-A1 Novel indole derivatives exhibiting chymase-inhibitory activities and process for preparation thereof CMA1, TPSD1, IDO1 KDM4E 1762/4885NQO2 1499/4885ALDH1A1 913/4885
US-20040231067-A1 Dyeing composition comprising a cationic tertiary para-phenylenediamine and heterocyclic coupler, methods and uses KRT18, CDC73, PYCR1 KDM4E 1620/4885NQO2 1067/4885ALDH1A1 1097/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.