Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL806814 | 0.79 | — | — | |
| SCHEMBL15065711 | 0.69 | — | — | |
| SCHEMBL15084407 | 0.69 | — | — | |
| SCHEMBL807471 | 0.66 | — | — | |
| SCHEMBL18360666 | 0.66 | ROCK2 (0.44) | — | |
| SCHEMBL15084357 | 0.65 | CHRNA7 (0.60) | FAAHPDE2AHDAC8HDAC6DRD2 | |
| SCHEMBL18360668 | 0.65 | PRMT5 (0.35) | FAAHMAPK1 | |
| SCHEMBL15065414 | 0.63 | — | — | |
| SCHEMBL15065068 | 0.63 | PIP5K1C (0.44) | — | |
| SCHEMBL14872679 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012036997-A1 | FUSED PYRAZOLE DERIVATIVES AS NOVEL ERK INHIBITORS | SCHERING CORPORATION (US) | 2012-03-22 | — | — | WO | disclosed |