Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 6/20 | 0.35 |
| ▸ | HRH1 | P35367 | 6/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | ACACB | O00763 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066212 | 0.92 | PTPN1 (0.37) | HRH2HRH1GPR119PTPN1ITGB3 | |
| SCHEMBL8073128 | 0.91 | HRH2 (0.36) | HRH2HRH1ACACBITGB3ITGA2B | |
| SCHEMBL8069233 | 0.85 | HRH2 (0.35) | HRH2HRH1GPR119ACACB | |
| SCHEMBL8073649 | 0.84 | ITGB3 (0.37) | HRH2HRH1ITGB3ITGA2B | |
| SCHEMBL8058055 | 0.83 | ELANE (0.36) | HRH2HRH1GPR119 | |
| SCHEMBL2897134 | 0.81 | GPR119 (0.45) | HRH2HRH1GPR119 | |
| SCHEMBL2897137 | 0.81 | GPR119 (0.45) | HRH2HRH1GPR119 | |
| SCHEMBL2897133 | 0.81 | GPR119 (0.45) | HRH2HRH1GPR119 | |
| SCHEMBL8072985 | 0.79 | ITGB3 (0.49) | HRH2HRH1ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8076479 | 0.79 | ITGB3 (0.49) | HRH2HRH1ITGB3ITGA2BSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |