Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LPO | P22079 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089797 | 0.84 | KMT2A (0.42) | KMT2AMEN1KDM4ECYP2D6MAPT | |
| SCHEMBL8076706 | 0.74 | LPO (0.36) | KMT2AMEN1LPO | |
| SCHEMBL8088192 | 0.68 | KDM4E (0.42) | KMT2AMEN1KDM4ECYP2D6MAPT | |
| SCHEMBL5093089 | 0.63 | LPO (0.43) | KMT2AMEN1KDM4ELPONPC1 | |
| SCHEMBL16153139 | 0.63 | ESR1 (0.35) | KMT2AMEN1CYP2D6MAPTNPC1 | |
| SCHEMBL12467059 | 0.62 | NR1H2 (0.35) | KMT2AMEN1CYP2D6MAPTLMNA | |
| SCHEMBL8084747 | 0.62 | LPO (0.41) | KMT2AMEN1KDM4EMAPTLPO | |
| SCHEMBL8088230 | 0.62 | TP53 (0.32) | NPC1LMNA | |
| SCHEMBL5722623 | 0.62 | LPO (0.41) | KMT2AMEN1KDM4EMAPTLPO | |
| SCHEMBL19723382 | 0.61 | BRD4 (0.46) | KMT2AMEN1KDM4EBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050536-A2 | 2-(Benz-)Imidazol-, 2-(Benz-)Oxazol- or 2-(Benz-)Thiazol-substituted Silanes | Wacker-Chemie GmbH (DE) | 2000-11-08 | — | — | EP | disclosed |