Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LPO | P22079 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089797 | 0.72 | KMT2A (0.42) | KDM4EKMT2ACYP2D6MEN1LPO | |
| SCHEMBL13766348 | 0.72 | ESR1 (0.37) | KDM4ECYP2D6TSHRLMNA | |
| SCHEMBL8076693 | 0.71 | LPO (0.43) | KDM4EKMT2ACYP2D6LPOBRD4 | |
| SCHEMBL8089840 | 0.70 | LPO (0.41) | KDM4EKMT2ACYP2D6LPO | |
| SCHEMBL8089847 | 0.70 | LPO (0.41) | KDM4EKMT2ACYP2D6LPO | |
| SCHEMBL3401057 | 0.68 | KDM4E (0.67) | KDM4EKMT2ACYP2D6MEN1BRD4 | |
| SCHEMBL8076687 | 0.68 | KMT2A (0.39) | KDM4EKMT2ACYP2D6MEN1LPO | |
| Hydrochloric Acid SCHEMBL29054527 | 0.67 | KDM4E (0.65) | KDM4EKMT2ACYP2D6MEN1BRD4 | |
| SCHEMBL6345915 | 0.64 | LPO (0.48) | KDM4EKMT2ACYP2D6MEN1LPO | |
| SCHEMBL25470313 | 0.63 | ACHE (0.43) | KDM4EKMT2AMEN1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050536-A2 | 2-(Benz-)Imidazol-, 2-(Benz-)Oxazol- or 2-(Benz-)Thiazol-substituted Silanes | Wacker-Chemie GmbH (DE) | 2000-11-08 | — | — | EP | disclosed |