Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPO | P22079 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | FDPS | P14324 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089840 | 0.74 | LPO (0.41) | LPOCHRNB2CHRNA4HTTKDM4E | |
| SCHEMBL8089847 | 0.74 | LPO (0.41) | LPOCHRNB2CHRNA4HTTKDM4E | |
| SCHEMBL6345915 | 0.72 | LPO (0.48) | LPOCHRNB2CHRNA4HTTKDM4E | |
| SCHEMBL8076693 | 0.71 | LPO (0.43) | LPOCHRNB2CHRNA4HTTKDM4E | |
| SCHEMBL6427486 | 0.71 | KDM4E (0.33) | HTTKDM4ETSHR | |
| SCHEMBL6829172 | 0.70 | LPO (0.46) | LPOCHRNB2CHRNA4HTTKDM4E | |
| SCHEMBL8088201 | 0.68 | LPO (0.36) | LPOCHRNB2CHRNA4KDM4EFDPS | |
| SCHEMBL5093089 | 0.67 | LPO (0.43) | LPOCHRNB2CHRNA4HTTKDM4E | |
| SCHEMBL4065142 | 0.66 | KDM4E (0.50) | LPOCHRNB2CHRNA4HTTKDM4E | |
| SCHEMBL8084747 | 0.65 | LPO (0.41) | LPOHTTKDM4EFDPSTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1050536-A2 | 2-(Benz-)Imidazol-, 2-(Benz-)Oxazol- or 2-(Benz-)Thiazol-substituted Silanes | Wacker-Chemie GmbH (DE) | 2000-11-08 | — | — | EP | disclosed |