Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.43 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089897 | 0.83 | HDAC6 (0.50) | HDAC6MAPTNSD2CYP1A2HSD17B10 | |
| SCHEMBL8076787 | 0.83 | KDR (0.40) | HDAC6MAPTTP53ALDH1A1HPGD | |
| SCHEMBL8084792 | 0.81 | NPSR1 (0.44) | HDAC6MAPTTP53CYP1A2ALDH1A1 | |
| SCHEMBL8090035 | 0.81 | SMN1; SMN2 (0.54) | MAPTCYP1A2CYP3A4CYP2C19HIF1A | |
| SCHEMBL8088268 | 0.81 | HSD17B10 (0.50) | MAPTCYP1A2CYP3A4CYP2C19HIF1A | |
| SCHEMBL8084757 | 0.79 | ALDH1A1 (0.49) | MAPTCYP1A2CYP3A4CYP2C19HIF1A | |
| SCHEMBL8088227 | 0.79 | DNMT1 (0.44) | HDAC6MAPTTP53HSD17B10ALDH1A1 | |
| SCHEMBL8084739 | 0.77 | ALDH1A1 (0.60) | MAPTCYP1A2CYP3A4CYP2C19HIF1A | |
| SCHEMBL8084741 | 0.77 | ALDH1A1 (0.50) | MAPTCYP1A2CYP3A4CYP2C19HIF1A | |
| SCHEMBL8084097 | 0.77 | HTR2C (0.48) | MAPTCYP1A2CYP3A4CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |