Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.49 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | EGFR | P00533 | 3/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | GCGR | P47871 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8089979 | 0.91 | CYP1A2 (0.51) | SMN1; SMN2CYP1A2MAPTALDH1A1HTT | |
| SCHEMBL8084075 | 0.88 | NR4A2 (0.52) | SMN1; SMN2NR4A2CYP19A1MAOBCYP1A2 | |
| SCHEMBL8084665 | 0.87 | CYP1A2 (0.57) | SMN1; SMN2MAOBCYP1A2EGFRGCGR | |
| SCHEMBL8084757 | 0.87 | ALDH1A1 (0.49) | SMN1; SMN2MAOBCYP1A2MAPTALDH1A1 | |
| SCHEMBL8088268 | 0.84 | HSD17B10 (0.50) | SMN1; SMN2NR4A1MAOBCYP1A2MAPT | |
| SCHEMBL8076747 | 0.82 | CYP1A2 (0.55) | SMN1; SMN2CYP1A2MAPTALDH1A1RAB9A | |
| SCHEMBL8076734 | 0.81 | HDAC6 (0.47) | MAOBCYP1A2MAPTALDH1A1GAA | |
| SCHEMBL8076711 | 0.80 | MAPT (0.51) | SMN1; SMN2CYP1A2MAPTALDH1A1HTT | |
| SCHEMBL8089846 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2CYP1A2MAPTALDH1A1HTT | |
| SCHEMBL8084810 | 0.80 | CHEK2 (0.46) | SMN1; SMN2MAOBCYP1A2EGFRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057447-A | BACTERICIDES FOR CAMPYLOBACTER | ZENYAKU KOGYO KABUSHIKI KAISHA (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0926139-A1 | QUINOLINE SULFIDE DERIVATIVES | ZENYAKU KOGYO KABUSHIKIKAISHA (JP) | 1999-06-30 | — | — | EP | disclosed |