Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.63 |
| ▸ | GAA | P10253 | 5/20 | 0.63 |
| ▸ | PRNP | P04156 | 3/20 | 0.58 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.58 |
| ▸ | PPARG | P37231 | 2/20 | 0.58 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.58 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12086597 | 0.86 | GAA (0.49) | KDM4EGAAPRNPRXFP1PPARG | |
| SCHEMBL8076792 | 0.84 | HTT (0.47) | KDM4EGAAPRNPRXFP1PPARG | |
| SCHEMBL12086639 | 0.83 | ALOX12 (0.55) | KDM4EGAAPRNPRXFP1PPARG | |
| SCHEMBL12086636 | 0.81 | NPSR1 (0.45) | KDM4EGAAPRNPRXFP1PPARG | |
| SCHEMBL9342946 | 0.80 | ALOX12 (0.49) | KDM4EGAAPRNPRXFP1PPARG | |
| SCHEMBL9172913 | 0.79 | NPSR1 (0.64) | KDM4EGAAPRNPRXFP1PPARG | |
| SCHEMBL29448052 | 0.79 | NPSR1 (0.64) | KDM4EGAAPRNPRXFP1PPARG | |
| SCHEMBL23397542 | 0.78 | LMNA (0.43) | KDM4EGAAPRNPRXFP1PPARG | |
| SCHEMBL11931773 | 0.78 | HTT (0.43) | KDM4EGAAPRNPRXFP1PPARG | |
| SCHEMBL11537833 | 0.77 | GAA (0.44) | KDM4EGAAPRNPRXFP1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4166131-A | ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANTIARTHRITIC AGENT | HEXACHIMIE SOCIETE ANONYME (FR) | 1979-08-28 | — | — | US | disclosed |