Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081379 | 0.87 | PTGS1 (0.51) | HPGDPTGS2PTGS1LMNASMN1; SMN2 | |
| SCHEMBL5692490 | 0.86 | KMT2A (0.52) | KMT2APTGS2PTGS1FAAHLMNA | |
| SCHEMBL4202325 | 0.85 | KMT2A (0.47) | HPGDKMT2APTGS2PTGS1FAAH | |
| SCHEMBL10527197 | 0.85 | KMT2A (0.47) | HPGDKMT2APTGS2PTGS1FAAH | |
| SCHEMBL8066957 | 0.84 | KMT2A (0.41) | HPGDKMT2APTGS2LMNAALDH1A1 | |
| SCHEMBL8076515 | 0.82 | BRD4 (0.49) | HPGDKMT2APTGS2SMN1; SMN2L3MBTL1 | |
| SCHEMBL6206998 | 0.81 | SMN1; SMN2 (0.41) | HPGDKMT2APTGS2PTGS1FAAH | |
| SCHEMBL8847526 | 0.79 | KMT2A (0.55) | HPGDKMT2APTGS2PTGS1LMNA | |
| SCHEMBL28270629 | 0.79 | KMT2A (0.46) | KMT2APTGS2PTGS1FAAHLMNA | |
| SCHEMBL8081453 | 0.78 | PTGS2 (0.58) | PTGS2PTGS1FAAHLMNAADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031629-A2 | Method of preparation of stereoisomeric carboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-30 | — | — | EP | disclosed |