Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 6/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.51 |
| ▸ | ELANE | P08246 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.45 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.45 |
| ▸ | THPO | P40225 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8076887 | 0.87 | HPGD (0.46) | PTGS1PTGS2SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL8076959 | 0.81 | ELANE (0.46) | ELANESMN1; SMN2HPGDALDH1A1MAPT | |
| SCHEMBL14307496 | 0.81 | PTGS1 (0.74) | PTGS1PTGS2ELANESMN1; SMN2HPGD | |
| SCHEMBL8066957 | 0.79 | KMT2A (0.41) | PTGS2HPGDALDH1A1LMNAHSD17B10 | |
| SCHEMBL8076971 | 0.79 | PTGS1 (0.51) | PTGS1PTGS2ELANESMN1; SMN2HPGD | |
| SCHEMBL801382 | 0.79 | PTGS2 (0.59) | PTGS1PTGS2ELANESMN1; SMN2HPGD | |
| SCHEMBL8076515 | 0.78 | BRD4 (0.49) | PTGS2SMN1; SMN2HPGDALDH1A1RAB9A | |
| SCHEMBL7704968 | 0.77 | PTGS2 (0.71) | PTGS1PTGS2SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL5313395 | 0.77 | PTGS2 (0.71) | PTGS1PTGS2SMN1; SMN2HPGDALDH1A1 | |
| SCHEMBL8021929 | 0.75 | PTGS2 (0.54) | PTGS1PTGS2ELANESMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031629-A2 | Method of preparation of stereoisomeric carboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-30 | — | — | EP | disclosed |