Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8066957 | 0.84 | KMT2A (0.41) | PTGS2ALDH1A1KMT2AHPGD | |
| SCHEMBL8076887 | 0.82 | HPGD (0.46) | L3MBTL1PTGS2ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL8081389 | 0.79 | BRD4 (0.45) | BRD4FFAR2L3MBTL1ALDH1A1MEN1 | |
| SCHEMBL8081453 | 0.79 | PTGS2 (0.58) | PTGS2 | |
| SCHEMBL1679062 | 0.78 | L3MBTL1 (0.54) | BRD4FFAR2L3MBTL1PTGS2HDAC4 | |
| SCHEMBL8081379 | 0.78 | PTGS1 (0.51) | PTGS2ALDH1A1SMN1; SMN2HPGDRAB9A | |
| SCHEMBL8076393 | 0.77 | CYP1A2 (0.49) | L3MBTL1ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27787971 | 0.77 | BRD4 (0.44) | BRD4FFAR2L3MBTL1ADRB2PTGS2 | |
| SCHEMBL8076660 | 0.76 | BRD4 (0.41) | BRD4FFAR2L3MBTL1ADRB2PTGS2 | |
| SCHEMBL8076618 | 0.76 | ACACB (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1031629-A2 | Method of preparation of stereoisomeric carboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2000-08-30 | — | — | EP | disclosed |