Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 7/20 | 0.59 |
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 3/20 | 0.53 |
| ▸ | MAOA | P21397 | 2/20 | 0.53 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8515760 | 0.95 | GAA (0.65) | GAAMAPTHTTALDH1A1LMNA | |
| SCHEMBL20390741 | 0.91 | GAA (0.70) | GAAMAPTHTTALDH1A1LMNA | |
| SCHEMBL31072419 | 0.90 | GAA (0.59) | GAAMAPTHTTALDH1A1HPGD | |
| SCHEMBL784951 | 0.87 | GAA (0.65) | GAAMAPTHTTALDH1A1LMNA | |
| SCHEMBL16748398 | 0.86 | GAA (0.45) | GAAMAPTHTTALDH1A1HPGD | |
| SCHEMBL785327 | 0.86 | GAA (0.54) | GAAMAPTHTTALDH1A1LMNA | |
| SCHEMBL4569551 | 0.85 | GAA (0.63) | GAAHTTALDH1A1LMNAAGTR1 | |
| SCHEMBL8723466 | 0.85 | MAPT (0.60) | GAAMAPTHTTALDH1A1LMNA | |
| SCHEMBL20808585 | 0.85 | KMT2A (0.65) | GAAMAPTHTTALDH1A1LMNA | |
| SCHEMBL20345019 | 0.84 | HTT (0.52) | GAAMAPTHTTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030832-A2 | ORGANIC MATERIALS STABILIZED BY COMPOUNDS CONTAINING BOTH AMINE AND HINDERED PHENOL FUNCTIONALITIES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 2000-08-30 | — | — | EP | claimed |
| WO-1999020686-A2 | ORGANIC MATERIALS STABILIZED BY COMPOUNDS CONTAINING BOTH AMINE AND HINDERED PHENOL FUNCTIONALITIES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-04-29 | — | — | WO | claimed |
| US-5834544-A | Organic materials stabilized by compounds containing both amine and hindered phenol functional functionalities | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1998-11-10 | — | — | US | claimed |
| EP-3071544-B1 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME | POLNOX CORP (US) | 2022-07-06 | — | — | EP | disclosed |
| EP-3071544-B1 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME | POLNOX CORP (US) | 2022-07-06 | — | — | EP | disclosed |
| US-11060027-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2021-07-13 | — | — | US | disclosed |
| US-20200392406-A1 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME | POLNOX CORPORATION | 2020-12-17 | — | — | US | disclosed |
| US-10683455-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2020-06-16 | — | — | US | disclosed |
| US-10683455-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2020-06-16 | — | — | US | disclosed |
| US-20190292454-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | POLNOX CORPORATION | 2019-09-26 | — | — | US | disclosed |
| US-20190292454-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | POLNOX CORPORATION | 2019-09-26 | — | — | US | disclosed |
| US-10294423-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | POLNOX CORPORATION (US) | 2019-05-21 | — | — | US | disclosed |
| US-20160289558-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | POLNOX CORPORATION (US) | 2016-10-06 | — | — | US | disclosed |
| US-20160289558-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | POLNOX CORPORATION (US) | 2016-10-06 | — | — | US | disclosed |
| US-20160289558-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | POLNOX CORPORATION (US) | 2016-10-06 | — | — | US | disclosed |
| EP-3071544-A2 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME | Polnox Corporation (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015077635-A2 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES METHODS OF MAKING AND USING THE SAME | POLNOX CORPORATION (US) | 2015-05-28 | — | — | WO | disclosed |
| EP-1030832-A2 | ORGANIC MATERIALS STABILIZED BY COMPOUNDS CONTAINING BOTH AMINE AND HINDERED PHENOL FUNCTIONALITIES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999020686-A2 | ORGANIC MATERIALS STABILIZED BY COMPOUNDS CONTAINING BOTH AMINE AND HINDERED PHENOL FUNCTIONALITIES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1999-04-29 | — | — | WO | disclosed |
| US-5834544-A | Organic materials stabilized by compounds containing both amine and hindered phenol functional functionalities | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1998-11-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11060027-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | LPO, GPX4, DUOX2 | GAA 1034/4885MAPT 2287/4885HTT 1761/4885 |
| US-10683455-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | LPO, GPX4, DUOX2 | GAA 1034/4885MAPT 2287/4885HTT 1761/4885 |
| US-20160289558-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | LPO, GPX4, DUOX2 | GAA 1016/4885MAPT 2179/4885HTT 1601/4885 |
| US-20190292454-A1 | Macromolecular Antioxidants Based On Dual Type Moiety Per Molecule: Structures, Methods Of Making And Using The Same | LPO, GPX4, DUOX2 | GAA 1034/4885MAPT 2287/4885HTT 1761/4885 |
| US-20200392406-A1 | MACROMOLECULAR ANTIOXIDANTS BASED ON DUAL TYPE MOIETY PER MOLECULE: STRUCTURES, METHODS OF MAKING AND USING THE SAME | LPO, GPX4, DUOX2 | GAA 1034/4885MAPT 2287/4885HTT 1761/4885 |
| US-10294423-B2 | Macromolecular antioxidants based on dual type moiety per molecule: structures, methods of making and using the same | LPO, GPX4, DUOX2 | GAA 1016/4885MAPT 2179/4885HTT 1601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.