Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.41 |
| ▸ | TUBB | P07437 | 3/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.41 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.41 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.41 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.41 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.41 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.41 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.41 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.41 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5992568 | 0.77 | GAK (0.48) | KCNH2PDGFRBPDGFRACYP2A6ERN1 | |
| SCHEMBL4459254 | 0.77 | KDM4E (0.59) | HDAC1MEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL6130391 | 0.76 | KDM4E (0.57) | HDAC1MEN1POLBKMT2A | |
| SCHEMBL4444229 | 0.76 | MEN1 (0.51) | KCNH2PDGFRBPDGFRACYP2A6ERN1 | |
| SCHEMBL8078437 | 0.75 | SMPD3 (0.52) | HDAC2GHSRTACR1MEN1KMT2A | |
| SCHEMBL8083575 | 0.74 | KDM4E (0.52) | KCNH2HDAC1HDAC2MEN1POLB | |
| SCHEMBL26414634 | 0.73 | ERN1 (0.50) | KCNH2PDGFRBPDGFRACYP2A6ERN1 | |
| SCHEMBL4685840 | 0.73 | NR4A2 (0.61) | HDAC1HDAC2PDGFRBPDGFRACYP2A6 | |
| SCHEMBL27703952 | 0.72 | ERN1 (0.49) | KCNH2PDGFRBPDGFRACYP2A6ERN1 | |
| SCHEMBL8526954 | 0.72 | PDGFRB (0.61) | KCNH2PDGFRBPDGFRACYP2A6ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836596-B1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEM CO INC (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0836596-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002257-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-01-23 | — | — | WO | disclosed |