Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 10/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 10/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27864586 | 0.80 | ALDH1A1 (0.66) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8616986 | 0.80 | HDAC2 (0.51) | HDAC1HDAC2HDAC3KCNH2 | |
| SCHEMBL21999630 | 0.80 | KCNH2 (0.64) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL23097942 | 0.76 | KCNH2 (0.64) | KDM4EALDH1A1MEN1KMT2AHDAC1 | |
| SCHEMBL7059675 | 0.76 | TNFRSF1A (0.51) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL4459254 | 0.76 | KDM4E (0.59) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL28278107 | 0.74 | ALDH1A1 (0.62) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL26414626 | 0.74 | ALDH1A1 (0.52) | KDM4EALDH1A1MEN1KMT2ANPC1 | |
| Hydrochloric Acid SCHEMBL6130391 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL8078586 | 0.74 | KCNH2 (0.45) | MEN1KMT2AHDAC1HDAC2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836596-B1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEM CO INC (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0836596-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002257-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-01-23 | — | — | WO | disclosed |