Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.52 |
| ▸ | GHSR | Q92847 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.41 |
| ▸ | KCNB1 | Q14721 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27409381 | 0.81 | SMPD3 (0.56) | SMPD3GHSRHDAC2ADRB2LOXL2 | |
| SCHEMBL22000048 | 0.78 | SMPD3 (0.56) | SMPD3ADRB2LOXL2ECE1TACR1 | |
| SCHEMBL22040486 | 0.78 | SMPD3 (0.60) | SMPD3HDAC2ADRB2LOXL2ECE1 | |
| SCHEMBL8234511 | 0.76 | PTGDR2 (0.52) | SMPD3ADRB2LOXL2ECE1TACR1 | |
| SCHEMBL8078586 | 0.75 | KCNH2 (0.45) | GHSRHDAC2TACR1MEN1KMT2A | |
| SCHEMBL15010747 | 0.75 | SMPD3 (0.60) | SMPD3ADRB2LOXL2ECE1TACR1 | |
| SCHEMBL7054724 | 0.74 | SMPD3 (0.52) | SMPD3ADRB2ECE1PTGDR2KCNB1 | |
| SCHEMBL29291643 | 0.74 | SMPD3 (0.52) | SMPD3ADRB2ECE1PTGDR2PDPK1 | |
| SCHEMBL8083575 | 0.74 | KDM4E (0.52) | HDAC2MAPK1SMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL8069251 | 0.72 | AGTR1 (0.47) | HCRTR1HCRTR2MAPK14SMOSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0836596-B1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEM CO INC (US) | 2000-08-23 | — | — | EP | disclosed |
| EP-0836596-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, Inc. (US) | 1998-04-22 | — | — | EP | disclosed |
| WO-1997002257-A1 | HYDRAZINE DERIVATIVES | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1997-01-23 | — | — | WO | disclosed |