Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8081691 | 0.83 | SCN4A (0.38) | SCN4AEPHX1TAAR1LTA4HTSHR | |
| SCHEMBL5679399 | 0.78 | HDAC3 (0.39) | SCN4AEPHX1TAAR1LTA4HTSHR | |
| SCHEMBL1033247 | 0.77 | SLC6A4 (0.43) | SCN4AEPHX1TAAR1LTA4HTSHR | |
| SCHEMBL8107481 | 0.77 | ALDH1A1 (0.41) | SCN4AEPHX1TAAR1LTA4HTSHR | |
| SCHEMBL16167284 | 0.76 | LTA4H (0.39) | SCN4ATAAR1LTA4HTSHRKCNA3 | |
| SCHEMBL1569929 | 0.76 | EPHX1 (0.60) | EPHX1TAAR1SLC6A4MAOAPTGS1 | |
| SCHEMBL28085523 | 0.76 | HRH1 (0.46) | SCN4AEPHX1TAAR1LTA4HSLC6A4 | |
| Hydrochloric Acid SCHEMBL6963695 | 0.74 | EPHX1 (0.58) | EPHX1TAAR1SLC6A4MAOAPTGS1 | |
| SCHEMBL19586897 | 0.74 | SCN4A (0.42) | SCN4AEPHX1TAAR1LTA4HKCNA3 | |
| SCHEMBL3227309 | 0.74 | SLC6A4 (0.41) | SCN4AEPHX1LTA4HSLC6A4MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0846679-B1 | Process for preparing 1,3-disubstituted urea | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-09-06 | — | — | EP | disclosed |
| US-5902899-A | Process for preparing 1, 3-disubstituted urea | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-05-11 | — | — | US | disclosed |